Genital Warts Treatment: Antiproliferative Therapies

Podophyllin resin 10%-25%

This is applied by the doctor onto the warts in a 10-25% suspension in tincture of benzoin.

• Disadvantage - has to be applied by the physician. Can be quite irritating. Care must be taken just to apply onto the wart itself. It cannot be used in pregnancy.

Podophylox 0.5% solution or gel

This is a purified podophyllin. This can be safely used by the patient. It is applied on the warts twice a day for 3 consecutive days in a week and then repeated 2 to 4 times. Clearance of warts occurs in about 40 to 70% of patients. The warts recur in up to 38% of patients

• Advantage - can be applied by the patient. Relatively inexpensive. Does not contain the mutagenic substances found in podophyllin resin.
• Dsadvantages - Inflammation causing burning,itching and pain can occur as can superficial ulceration of the skin. It should not be used in pregnancy

• Treatment Options and Objectives
• Destruction/Excision Therapies
• Antiproliferative Therapies
• Immunomodulatory Therapy
• Prophylaxis
• Combination Therapy
• Treatment Summary and Conclusion
• Genital Warts: Treatment Algorithm